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Brown MJ, Willis T, Omalu B, Leiker R
A literature and patent review published in Pharmaceuticals (MDPI) summarizes that BPC-157 demonstrates a desirable safety profile in preclinical research, with only a few side effects reported across animal studies, and documents its broad activity across tissue injury, inflammatory and CNS-adjacent research models via VEGFR2-Akt-eNOS angiogenic pathways and nitric oxide signaling
Certain medical conditions, including uncontrolled high blood pressure, kidney disease, kidney failure, and active heart conditions , may make IV therapy unsuitable
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